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The influence of environment and origin on brain resident macrophages and implications for therapy

Microglia are the tissue-resident macrophages ... contributions of both brain environment and developmental history to the transcriptomic identity of microglia. Here we review this emerging literature ... read more

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The brain's rejuvenating cells

A unique immune cell type has been discovered, which may lead to a future treatment for Alzheimer's disease, say investigators. Alzheimer's disease is a neurodegenerative disease manifested by various ... read more

The influence of the microbiome on respiratory health

The revolution in microbiota research over the past decade has provided invaluable knowledge about the function of the microbial species that inhabit the human body. It has become widely accepted that ... read more

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What The Evidence Shows About Patient Activation: Better Health Outcomes And Care Experiences; Fewer Data On Costs

Judith H. Hibbard ( [email protected]) is a senior researcher at the Health Policy Research Group, Institute for Sustainable Environments, and a professor emerita in the Department of Planning, Public ... read more

Fungi cause brain infection and impair memory in mice

albicans that would not cause severe disease, but might carry implications ... damage the brain. "We thought that yeast would not enter the brain, but it does," Corry said. "In the brain, the yeast ... read more

Fathers’ Roles in the Care and Development of Their Children: The Role of Pediatricians

Particular emphasis is placed on (1) fathers’ involvement across childhood ages and (2) the influence of fathers’ physical and mental health on their children. Implications and ... have legal custody ... read more

Microglia and early brain development: An intimate journey

This Review focuses on the brain, where the early ... the presence of long-lived resident macrophages that originate in early embryogenesis (Fig. 1). These data indicate that the microglial population ... read more

Unpacking lactate's role in the Warburg effect

In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use energy differently than healthy cells. The research builds on an already ... read more

EMD Serono to Present New Data on Mavenclad®, Rebif® and the Investigational Therapy Evobrutinib at the AAN Annual Meeting 2019

The company will present a total of 20 abstracts (18 posters and two platform presentations), including data on MAVENCLAD ® (cladribine) tablets, the investigational therapy evobrutinib ... 1a as ... read more

Host-Gut Microbiota Metabolic Interactions

Extrinsic environmental factors (such as antibiotic use, diet, stress, disease, and injury) and the mammalian host genome continually influence the diversity and function of the gut microbiota with ... read more

Macrophages Are the Ultimate Multitaskers

13 A similar process also guides neurons and blood vessels in the developing brain. Resident macrophages in the brain ... ability to rapidly change according to environmental conditions might have ... read more

Power of the Placebo

Sarah Lidstone has a long history with the medical world ... Lidstone led a rather odd brain-imaging experiment. She brought 40 patients with mild Parkinson’s into the lab for a simple drug therapy ... read more

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