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Teratomaderived Stem Cells Rebuild Muscle In Model Of Muscular Dystrophy - Latest News


Muscle stem cells can drive cancer that arises in Duchenne muscular dystrophy

People with Duchenne muscular dystrophy ... demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD—and identified two genes linked to the tumor's growth. The rese... read more

Mouse model of muscular dystrophy points finger at stem cells

Stanford researchers have devised the first mouse model of Duchenne muscular dystrophy ... although the muscle damage is caused by a mutation in the dystrophin gene, symptoms occur because the muscle ... read more

Burnt sugar-derivative reduces muscle wasting in fly and mouse models of muscular dystrophy

A trace substance in caramelized sugar, when purified and given in appropriate doses, improves muscle regeneration in a mouse model of Duchenne ... muscles of mice with the muscular dystrophy mutation ... read more

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Stem cells used to treat muscular dystrophy in mice

Harvard Stem Cell ... that skeletal muscle precursor cells could function as adult stem cells and that transplantation of these cells could both repair muscle tissue and regenerate the stem cell pool ... read more


Duchenne muscular dystrophy is ultimately a stem cell disease

The longer telomeres normally found in mice apparently give their muscle stem cells greater staying power and a greater capacity to repair the damage ... by this form of muscular dystrophy, the resear... read more

Duchenne muscular dystrophy: How muscle cells journey to the dark side

Promoting repair ... by special cells called fibro-adipogenic progenitors (FAPs). Researchers already know these cells have a dark side–they are also responsible for the muscle wasting and scarring th... read more

Scientists speed up muscle repair, could help fight dystrophy

Athletes, the elderly and those with degenerative muscle disease would all benefit from accelerated muscle repair. When skeletal muscles are injured, muscle stem cells wake ... found that in a mouse m... read more

Cedars-Sinai Researchers Say Findings Lay Groundwork for Testing of CAP-1002 in Patients with Duchenne Muscular Dystrophy

The CDCs used in the study published in Stem Cell Reports were manufactured at Cedars-Sinai. The study was funded in part by a grant from Coalition Duchenne. Duchenne muscular dystrophy is a devastati... read more

Purified stem cells restore muscle in mice with muscular dystrophy

Those stem cells allowed the treated muscle to undergo subsequent rounds of injury repair, they found ... Mice lacking dystrophin, also known as mdx mice, are a model for Duchenne Muscular Dystrophy, ... read more

Reprogrammed human adult stem cells rescue diseased muscle in mice

The researchers then used a sophisticated genetic technique to repair ... a mouse model of muscular dystrophy. “These data demonstrate that genetically engineered blood or muscle-derived CD133+ cells ... read more

Aging Muscles May Be Restored by Discovery of a Key to Making Muscle

The technique also creates a sustainable pool of muscle stem cells needed to support multiple rounds of muscle repair. There are two important ... used normally aged mice and mice models of a form of ... read more

Stem cells faulty in Duchenne muscular dystrophy, researchers find

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive ... cycle,” Rando said. “As the muscle stem cells become less able to regenerate new muscle, the tissue is less ... read more



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