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Study: Chemotherapy Drugs May Promote Muscle Mitochondrial Dysfunction - Latest News


Chemotherapy may lead to mitochondrial dysfunction in skeletal muscle

Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction ... some people with breast cancer experience through the course of disease treatment. The study is published ahe... read more

Exercise, fasting help cells shed defective proteins

The lab’s previous research found that cAMP-stimulating drugs enhanced the destruction ... quality control,” he said. Harvard study shows how intermittent fasting and manipulating mitochondrial networ... read more

Technique could help identify patients who would suffer chemo-induced heart damage

These cells provide researchers with a sorely needed platform to study the effects of doxorubicin exposure on human heart muscle cells, and may allow them to one day predict which patients should avoi... read more

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Don’t Be a Zombie: Senolytics, Exercise and Fasting Fight Off Senescent Cells

Based on a 2010 study from the Journal of the American Geriatrics Society, 45% of people over the age of 85 today are frail, often suffering physical dysfunction and decreased mobility that may lead t... read more


NeuroVive's KL1333 Receives FDA Orphan Drug Designation for Treatment of Mitochondrial Diseases

Orphan drug designation (ODD) will give the KL1333 program extra access to regulatory and scientific advice and interactions at the FDA and may ... dysfunction in respiratory complex I and to NVP025, ... read more

Safety of Systemic Chemotherapy in a Patient With Mitochondrial Myopathy and Non–Small-Cell Lung Cancer

mtDNA mutations may lead to the coexistence of wild-type and mutated mitochondrial ... and did not increase significantly over time (Fig 1; AUC, area under the curve). Tumor assessment after three cyc... read more

Metabolomics Study Suggests Chronic Fatigue Syndrome May Be Oxidative Stress/Low Oxygen Disease

This study ... increase the prediction confidence and will reveal whether plasma metabolomics may serve as a reliable tool for objective identification and monitoring of ME/CFS patients.” Translation ... read more

Chemo-Boosting Drug Discovered for Leukemia

In this study, these drugs reversed bone marrow leaks in tissue from mice and humans, and also boosted chemotherapy effects. Since these drugs are already in clinical trials for other applications, th... read more

Senolytic Drugs Increase Lifespan, Improve Physical Function in Aging Mice

Senescent cells increase ... study published this week in the journal Nature Medicine, a team of researchers found that treatment with a combination of two senolytic drugs — dasatinib plus quercetin — ... read more

Extended Chemo Extends Life for Children With Rare Cancer

SUNDAY, June 3, 2018 (HealthDay News) -- Children suffering from rhabdomyosarcoma, a rare cancer of the muscle tissue, may have better chances for a cure if they have extended chemotherapy, a new stud... read more

About Muscle Tremors After Cancer Treatments

The more you know about muscle tremors after cancer treatments ... Legs and arms may also be affected. The American Cancer Society lists the following classes of chemotherapy drugs as the ones most li... read more

Cholesterol-lowering drug may reduce exercise benefits for obese adults, study finds

Statins, the most widely prescribed drugs worldwide, are often suggested to lower cholesterol and prevent heart disease ... to a 1.5 percent increase among participants also prescribed statins. Additi... read more



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