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Study: Chemotherapy Drugs May Promote Muscle Mitochondrial Dysfunction - Latest News

Study: Chemotherapy drugs may promote muscle mitochondrial dysfunction

Chemotherapy drugs to treat breast cancer may promote muscle mitochondrial dysfunction, according to new research. Dysfunctional mitochondria, the energy centers of the cells, may contribute to fatigu... read more

Breast cancer survivors, who lose muscle mass, can benefit from strength training, studies suggest

But, survivors are still left to struggle with many adverse side effects from the disease ... chemotherapy and hormonal suppression drugs that are used to suppress hormones that may have fueled ... read more

Oxygen deprivation counters deadly mitochondrial disease in animals

But biology is complicated, and researchers hoping to treat diseases in which our cells’ energy-providing machinery is faulty now suggest the opposite may ... [Food and Drug Administration]–approved t... read more

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Senolytic Drugs Increase Lifespan, Improve Physical Function in Aging Mice

Senescent cells increase ... study published this week in the journal Nature Medicine, a team of researchers found that treatment with a combination of two senolytic drugs — dasatinib plus quercetin — ... read more

Researchers identify new drugs that could help prevent hearing loss

A team of researchers led by Dr. Jian Zuo screened over 4,000 drugs for their ability to protect cochlear cells from the chemotherapy ... mitochondria. "The robust protection conferred by one-time loc... read more

Do Statins Make It Tough to Exercise?

For years, physicians and scientists have been aware that statins, the most widely prescribed drugs in the world, can cause muscle ... dysfunction; mitochondrial respiratory rates were about 25 percen... read more

Study: Brain energy crisis may spark Parkinson's

WASHINGTON -- Parkinson's disease may stem from an energy crisis in the brain ... who wasn't involved with the new study. Beal said scientists already are planning first-stage tests to see if a drug n... read more

Fasting-like diet turns the immune system against cancer

The study was published ... made it easier for the chemotherapy drugs to attack the cancer. Longo said it’s unclear if the diet-prompted response in the immune system is an evolved mechanism to protec... read more

Another 'smart' cancer drug can have toxic effects on the heart

Another FDA-approved targeted cancer drug, sunitinib (Sutent, Pfizer), may be associated with cardiac toxicity ... therapy over the long-term,” says Chen. “In this study, the cardiac dysfunction and h... read more

The New York Times

An important new study suggests that statins, the cholesterol-lowering medications that are the most prescribed drugs in the world, may ... muscle tissue, they found notable differences in the levels ... read more

Mitochondrial DNA and nuclear DNA: Not so independent after all

Understanding the cell’s inner workings opens opportunities for medical advances that can help save lives. The study appears ... of age-related disease and, perhaps one day, new mitochondria-based tre... read more

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