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Sglt2s Tops For Heart Failure Risk Reduction - Latest News

DECLARE-TIMI 58: Dapagliflozin Cuts Heart Failure in Diabetes

I think after the DECLARE-TIMI 58 trial we can definitely now say the biggest benefit of the SGLT2 inhibitors is on the prevention of heart failure, and the reduction ... risk factors for CVD were ran... read more

New Novartis study supports Entresto as foundational HFrEF therapy and in-hospital initiation in appropriate stabilized heart failure patients

1 In a pre-specified exploratory analysis of PIONEER-HF, Entresto also showed a significant 46% reduction in the risk of a composite of death, heart failure ... the world's top companies investing ... read more

Clinically Meaningful Outcome in NIH Trial of MPC-150-IM for Heart Failure LVAD Recipients Provides Pathway for Potential Regulatory Approval

Under the RMAT designation, Mesoblast received specific guidance from the FDA that reduction ... these very high-risk patients provides a potential pathway to bring our heart failure product ... read more

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Canvas Paints A Mixed Picture For J&J's Invokana

But an increased risk of amputation could see Invokana lose market share to the other SGLT2s, particularly Jardiance ... Most of the benefit was powered by a reduction in heart failure, and the trial ... read more

Bariatric Surgery Reduces Later Heart Failure Deaths

NASHVILLE, Tenn — Bariatric surgery may dramatically cut the risk for later death associated ... sample of patients hospitalized for heart failure, were presented November 13 here at Obesity Week 2018 ... read more

Bariatric surgery shrinks heart failure risk in severely obese

“Most likely, reducing obesity and those secondary risk factors is what likely led to reduction ... heart failure by almost half after four years. During the procedure, surgeons reduce the stomach to ... read more

Lilly trumpets Trulicity heart data in face-off with Novo Nordisk

The LEADER trial of Victoza also showed a 13% MACE risk reduction, for example ... showing that the drug was able to reduce the risk of hospitalisation for heart failure by 44% compared to DPP4 inhibi... read more

Javed Butler Part 4, How Do SGLT2 Inhibitors Impact Heart Failure

For heart failure, it’s consistent. With EMPA-REG trial, 35% or so reduction in heart failure risk. With CANVAS ... Freed: So, we know how SGLT2s work when it comes to reducing blood sugars. It increa... read more

Quantum Genomics Announces Excellent Topline Results from Phase 2b NEW-HOPE Study Evaluating Firibastat for Arterial Hypertension

Quantum Genomics (Euronext Growth - FR0011648971 - ALQGC), a biopharmaceutical company specializing in the development of a new drug class that directly targets the brain to treat hypertension and hea... read more

Amarin Corporation PLC (AMRN) CEO John Thero Presents Primary REDUCE-IT Trial Results Following Presentation at 2018 Scientific Sessions of American Heart Association ...

Some key exclusion criteria, again, the full list is contained in the NEJM related documents included severe Class 4 heart failure ... results in a relative risk reduction of 24.8%, gives you ... read more

5 Top Supplements for a Healthy Heart

The NHS line is that niacin may be offered to people with a high triglyceride level, but they warn that it should be monitored carefully and not be used by those with diabetes, liver disease, digestiv... read more

New link found between alcohol, genes and heart failure

The overall size of the heart ... be at risk too, explained Dr. James Ware, study author from the National Heart and Lung Institute at Imperial. This MRI image shows a heart with the condition alcohol ... read more

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