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SGLT-2s Tops for Heart Failure Risk Reduction

SGLT-2 inhibitors were the favored diabetes treatment for heart failure risk reduction in a systematic review and meta-analysis, researchers said. "Gliflozin" drugs showed the largest reduction for ... read more

AstraZeneca's Farxiga scores in kidney outcomes study

Sunday at the American Diabetes Association annual meeting, the British drugmaker trotted out results from an outcomes study, dubbed Declare, that showed Farxiga could trigger a 47% reduction in the ... read more

HCA Healthcare/HealthONE’s Swedish Medical Center Receives Get With The Guidelines-Heart Failure Gold Plus Quality Achievement Award

These measures include evaluation of the proper use of medications and aggressive risk-reduction therapies. Before discharge, patients should also receive education on managing their heart failure and ... read more

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Canvas Paints A Mixed Picture For J&J's Invokana

But an increased risk of amputation could see Invokana lose market share to the other SGLT2s, particularly Jardiance ... Most of the benefit was powered by a reduction in heart failure, and the trial ... read more

CardioMEMS heart failure sensor reliably safe, effectively reduces hospitalizations

as these patients are at very high risk of hospitalizations and complications." The primary efficacy endpoint was heart failure hospitalization rates in the year after the sensor was implanted ... read more

DECLARE-TIMI 58: Dapagliflozin Cuts Heart Failure in Diabetes

I think after the DECLARE-TIMI 58 trial we can definitely now say the biggest benefit of the SGLT2 inhibitors is on the prevention of heart failure, and the reduction ... risk factors for CVD were ... read more

Bariatric surgery shrinks heart failure risk in severely obese

“Most likely, reducing obesity and those secondary risk factors is what likely led to reduction ... heart failure by almost half after four years. During the procedure, surgeons reduce the stomach to ... read more

The simple habit that can reduce men's risk of heart failure

Certain types of moderate physical activity, such as walking and bicycling for 20 minutes per day, were associated with the largest reduction in heart failure risk, the study authors ... wrangle over ... read more

Detailed findings from CAROLINA® outcome trial support long-term cardiovascular safety profile of Tradjenta®

The findings from CAROLINA complement the results from CARMELINA ™, which demonstrated similar long-term cardiovascular safety for Tradjenta compared with placebo, including no increased risk of ... read more

ACC: AstraZeneca unveils more SGLT2 heart benefits with latest batch of real-world data

At last year’s ACC meeting, AstraZeneca presented real-world data showing that SGLT2s could top their diabetes drug peers at paring down the risk of hospitalizations for heart failure and deaths from ... read more

Once-Weekly Dulaglutide Benefit in REWIND, Longest CVOT to Date

After top-line ... or an urgent heart failure visit, and all-cause mortality. The primary composite outcome occurred in 594 patients (12.0%) in the dulaglutide group and in 663 patients (13.4%) in the ... read more

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