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SGLT2 Inhibitors: Is This the Start of a New Era?

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a relatively new class of antihyperglycemic agents that lower blood glucose by enhancing urinary excretion of glucose. [1] This mechanism of ... read more

Achillion Reports Positive Interim Data for ACH-4471 Phase 2 Combination Trial with Eculizumab at The New Era of Aplastic Anemia and PNH Meeting

trial assessing the safety and effectiveness of its oral small molecule factor D inhibitor ACH-4471 in combination with intravenous eculizumab at The New Era of Aplastic Anemia and PNH Meeting in ... read more

Watch out, Dupixent. Pfizer's new JAK inhibitor could come after your eczema market

Pfizer’s FDA-approved JAK inhibitor Xeljanz is currently struggling ... Dupixent ushered in a new era for moderate-to-severe atopic dermatitis in 2017 when it became the first biologic approved in the ... read more

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World’s first ‘Darwinian’ cancer drug programme aims to deliver step change in cancer treatment

“We’re especially excited by the potential of APOBEC inhibitors to slow down evolutionary diversity and drug resistance, and ensure our existing cancer drugs work for patients for much longer. “We ... read more


American College of Cardiology recommends empagliflozin as preferred SGLT2 inhibitor for adults with type 2 ...

A new Expert ... as the preferred SGLT2 inhibitor for its proven benefit in reducing the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease. The ... read more

ACC recommends empagliflozin as preferred SGLT2 inhibitor for adults with type 2 diabetes

A new Expert ... as the preferred SGLT2 inhibitor for its proven benefit in reducing the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease. The ... read more

Oral SGLT2 Inhibitors and You

and it’s important to pay attention to how you react when you start taking a new drug. You can help avoid side effects — common and serious — by alerting your doctor to any underlying health ... read more

Achillion Reports First Quarter 2019 Financial Results

“We made significant progress advancing our portfolio of oral factor D inhibitors in the first quarter of 2019 ... accepted for presentation at the New Era of Aplastic Anemia and PNH meeting ... read more

Decoding the signs of response to cancer immunotherapy

Immune checkpoint inhibitors (ICIs) work by interfering with the mechanism ... based in North Carolina, sees these tests as the start of a new era for NGS in the clinic. “The flexibility of NGS to ... read more

Fear: The big inhibitor of innovation and transformation

Questions that are commonly asked include: Where do we start? How do we structure ... will emotionally embrace the new learning and ways of working that need to occur? How do we minimize one of the ... read more

SGLT2 inhibitors in Type 1 Diabetes: What Are the Risks?

The other issue is that [SGLT2 inhibitors] are used widely by primary ... very carefully as we move into a new era. * A second medication, the oral SGLT1/2 inhibitor sotagliflozin (Sanofi) has also ... read more



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