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Sglt Inhibitors Explored As Type 1 Diabetes Treatment - Latest News

FDA warns about rare occurrences of a serious infection of the genital area with SGLT2 inhibitors for diabetes

SGLT2 inhibitors are FDA-approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes. SGLT2 inhibitors lower ... so it is important to seek treatment right away. Health ... read more

Big Data Confirm Type 2 Diabetes Treatment Approach

"Large-scale characterization of the effectiveness of type 2 diabetes ... treatment in addition to metformin. Only sulfonylureas, DPP-4 inhibitors, and thiazolidinediones were examined because not eno... read more

Vaginal candidiasis more likely with real-world use of SGLT2 inhibitors vs. clinical trials

Women with type 2 diabetes ... inhibitors and had no symptoms of vaginitis. Participants self-administered a vaginal swab before (baseline) and at 6 and 12 months after beginning SGLT2 inhibitor thera... read more

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Diabetes Drug Linked to Genital Infection, but Experts Downplay Danger

FDA officials issued a warning about SGLT2 inhibitors and a rare ... formulated for use in patients with type 2 diabetes, but they have also proven effective in reducing blood glucose levels in patien... read more


AstraZeneca presents further data showing the interconnectivity between cardiovascular and renal risks in diabetes at EASD 2018

as well as the unmet need in type-1 diabetes, where we are at the forefront of advancing treatment for patients. We are constantly pursuing science to advance the management of cardiovascular, renal a... read more

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

The Food and Drug Administration (FDA) has issued a warning regarding rare cases of necrotizing fasciitis of the perineum associated with sodium-glucose cotransporter-2 (SGLT2) inhibitors, a class of ... read more

WHO Issues Cost-Conscious Diabetes Treatment Guidelines

Specifically addressing treatment intensification after metformin in type 2 diabetes and use of ... thiazolidinediones, SGLT2 inhibitors, and dipeptidyl peptidase-4 [DPP-4] inhibitors." Glucagonlike p... read more

One class of drug used to treat type 2 diabetes may not reduce the risk of death when compared with placebo

One class of drug used to treat type 2 diabetes may not reduce ... studied three types of diabetes treatment: sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 (GLP-1) agonis... read more

Novo Nordisk Could Benefit From Latest FDA Warning

The FDA recently issued a warning about the linking of Fournier's gangrene with SGLT2 inhibitors used in the treatment of type-2 diabetes. Novo Nordisk claims that its GLP-1 analogues are better ... read more

FDA warns class of diabetes drugs may cause genital gangrene

30 (UPI) --The U.S. Food and Drug Administration has issued a warning that a class of type 2 diabetes drugs in ... an estimated 1.7 million patients received a dispensed prescription for an SGLT2 inhi... read more

New class of type 2 diabetes drug associated with rare, life-threatening outcome

A new class of drugs, known as SGLT2 inhibitors, is increasingly being prescribed for the treatment of type 2 ... is usually associated with type 1 diabetes - it's very uncommon for people with type 2 ... read more

Upcoming Conversation With An Expert: Understanding The Potential Of Lexicon's Sotagliflozin As A Novel Treatment For Diabetes

Type ... to SGLT-1 in the presence of an SGLT-2 inhibitor. (Abdul-Ghani et al. Diabetes. 2013) Combined with its ability to combat hypertension and obesity, sotagliflozin’s efficacy in treating diabet... read more

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