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Long-term DPP4-inhibitor use not tied to fracture risk in T2DM

(HealthDay)—For patients with type 2 diabetes mellitus (T2DM), long-term use of dipeptidyl peptidase-4 inhibitors (DPP4-Is) is not associated with fracture risk, according to a study published online ... read more

Merck (MRK) Will Present JANUVIA, Diabetes Pipeline, Other Data at 76th Scientific Sessions of the ADA

JANUVIA has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk ... Use caution in a patient with a history ... read more

Johnson & Johnson : Janssen Presents New Data Showing INVOKANA® (canagliflozin) is Associated with Greater Blood Glucose Control and Treatment Adherence Compared to DPP-4 ...

For the RW analysis, the investigators matched patients taking INVOKANA (624 patients) with those taking a DPP-4 inhibitor ... (fractures): Bone fractures have been seen in patients taking INVOKANA. T... read more

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Eli Lilly & Co. (LLY) John C. Lechleiter on Q2 2016 Results - Earnings Call Transcript

At ACR, along with Incyte, we presented data for baricitinib in rheumatoid arthritis from the Phase III long-term extension ... that Trajenta, a DPP-4 inhibitor, reduced blood sugar in adults with typ... read more


Haemodialysis-induced hypoglycaemia and glycaemic disarrays

Conditions that are associated with an increased risk ... As use of repaglinide or mitiglinide is rarely accompanied by hypoglycaemia, these agents are attractive therapeutic options for patients on d... read more

Weekly diabetes drug provides similar benefits to daily version

Long-term DPP4-inhibitor use not tied to fracture risk in T2DM More information: Ronald Goldenberg et al. Randomized clinical trial comparing the efficacy and safety of treatment with the once-weekly ... read more

Best Treatments for Type 2 Diabetes

Another type of test can be done at any time (not ... long-term complications. Proper treatment that keeps blood sugar in the normal range, combined with aggressive treatment to keep blood pressure an... read more

The gut–renal axis: do incretin-based agents confer renoprotection in diabetes?

Diabetic nephropathy is the leading cause of end-stage renal disease worldwide, and is associated with a high risk of cardiovascular morbidity ... used in the treatment of type 2 diabetes mellitus (T2... read more



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