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Glitches In Dna Replication Have Important Implications For Treating Cancer - Latest News

Glitches in DNA replication have important implications for treating cancer

USC researchers peering deep inside a living cell have discovered something surprising: Its system for preventing genetic damage linked to diseases can fail so badly that the cell would be better off ... read more

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USC Study Reveals Gene `Glitch’ With Implications For Cancer Treatments

USC researchers studying cell division discovered a specific gene defect that has important implications for treating cancer and other genetic diseases, the university announced Monday. The lab study ... read more

USC scientists examine the impact of a very specific defect in DNA replication

The new lab study finds an unexpected glitch in a gene that supervises mitosis, one that has important implications for cancer treatment. read more

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New Lab Study Finds Unexpected Glitch in Mitosis Gene

The findings have important implications for treating cancer. In addition, glitches in DNA replication lead to other genetic diseases, including birth defects, autism and neurological impairments. A ... read more

The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma

Proteasome inhibitors have provided a significant advance in the treatment of multiple myeloma ... E3 ubiquitin ligases in cancer and implications for therapies. Cancer Metastasis Rev. 2017;36:683 ... read more

A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity

DNA methylation is considered a stable epigenetic mark, yet methylation patterns can vary during differentiation and in diseases such as cancer ... context can have different implications for ... read more

Can a Vaccine for Covid-19 Be Developed in Record Time?

Barouch: Currently there are no approved DNA vaccines or RNA vaccines. Some of them have been tested in small ... vaccine the way that a cancer treatment, ulcer drug or cholesterol-lowering ... read more

Xiaolan Zhao: Overview

As mutations in Smc5/6 subunits have been found in about 10 percent of cancer genomes sequenced thus far, understanding how the complex functions harbors important implications for diagnosing and ... read more

This Week in Science

A promising drug target is the viral main protease M pro, which plays a key role in viral replication ... using chloroplast DNA sequencing give conflicting estimates about when flowering plants first ... read more

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