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Genetically Engineered 3d Human Muscle Transplant In A Murine Model - Latest News

Genetically engineered 3-D human muscle transplant in a murine model

Representative 3D ... 3-D muscle grafts to a clinical setting. Explore further: New approach reduces immune response to tissue engineered vascular grafts More information: Luba Perry et al. Geneticall... read more

3D Printed Human Organs and the Debate on Applicable Patent Law

Perhaps the most significant of these challenges involves the human biology, and the need to integrate patient-specific data to model and engineer a tissue structure that will not be rejected by the h... read more

Partnership Puts IU Closer to 3D Printing Transplantable Organs

for human transplantation. The IU researchers use genetically-engineered pig liver cells to 3D print pig liver models. “We can [3D] print the miniature pig organ models within a day, grow and mature t... read more

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Cardiac differentiation of pluripotent stem cells and implications for modeling the heart in health and disease

This genetic blueprint for heart development is crucial for proper identification and characterization of human pluripotent stem cell ... complex cardiac disorders and to engineering three-dimensional ... read more

Mouse model of human immune system inadequate for stem cell studies

Optimized models are ... the animals have been engineered to have a human, rather than a murine, immune system. Researchers have relied upon the animals for decades to study, among other things, the i... read more

Neuroengineering in three-dimensional brain-like microenvironments

An illustrated model ... 3D microenvironment can boost direct neuronal reprogramming. Credit: Nature Biomedical Engineering, doi: 10.1038/s41551-018-0260-8 Neuroscientists have recently shown that bra... read more

3D Bioprinters Could Make Enhanced, Electricity-Generating 'Superorgans'

You can bioprint "an organ that is going to be part of the human body and generate electricity that can run the heart." Already, a 3D ... mini organ model lighting a bulb might be feasible in five yea... read more

Researchers engineer therapeutic skin grafts for diabetic mice

Therapeutic human ... to the point where 3D skin organoids can be grown in vitro, research groups are exploring other clinical uses for the technology. One hurdle has been a lack of mouse models for t... read more

Buy Celyad And Get In On The CAR-T Space In Solid Tumors: Medicine's Next Frontier

In murine models in in vivo studies ... I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this articl... read more

Stem Cells: the Basics

A form of gene therapy has been combined with stem cell transplant to cure the rare childhood condition known as "Bubble Boy" disease, or severe combined immunodeficiency. Recently, grafts from geneti... read more

Human tissues in a dish: The research and ethical implications of organoid technology

Growing functional human tissues and organs would provide ... disease research strategies commonly involve the generation of animal models. Laboratory animals, typically mice, are genetically modified ... read more

Gene therapy via skin could treat many diseases, even obesity

"We resolved some technical hurdles and designed a mouse-to-mouse skin transplantation model in animals with intact ... "It took us a few years to optimize our 3D skin organoid culture system." This s... read more

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