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Exercise Pathway That Regulates Muscle Remodeling May Have Implications For Metabolic Diseases - Latest News


Exercise Pathway That Regulates Muscle Remodeling May Have Implications for Metabolic Diseases

Scientists at the Joslin Diabetes Center have identified a molecular switch that appears to help direct whether we build muscle mass, or develop better aerobic capacity in response to exercise. The ... read more

JNK regulates muscle remodeling via myostatin/SMAD inhibition

We conclude that JNK acts as a key mediator of muscle remodeling during exercise via regulation of myostatin/SMAD signaling. As a means to discover the molecular mechanisms that regulate endurance ... ... read more

Muscles can 'ask' for the energy they need

They also discovered that this circuit is dependent on circadian rhythms, which could have implications ... for the energy they need: Research illuminates the pathway that gets fuel to muscles ... read more

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How to reap the benefits of exercise: It's in the genes

Exercise triggers TFEB entering ... "Our discovery of a central pathway that regulates muscle metabolism, use of glucose and mitochondrial function may have important implications in the study of ... read more


Exercise may fight depression in older adults, study suggests

Many people with depression have been found to have low levels of serotonin in the blood. Tryptophan metabolism happens almost completely through the kynurenine pathway, a "metabolic ... the muscles ... read more

Researchers Identify Drugs that Enhance Exercise Endurance

HHMI researchers have identified ... a subset of exercise-induced genes, but activating both pathways (by combining GW1516 with exercise) activated a larger group of genes. Many of those genes ... read more

Skeletal muscle mitochondrial remodeling in exercise and diseases

Notably, exercise counteracts the effects of many chronic diseases on skeletal muscle mitochondrial function. Recent studies have revealed a finely tuned ... state of knowledge relevant to the dynamic ... read more

How exercise reduces belly fat in humans

"The signaling pathways ... its implications," Wedell-Neergaard says. In the meantime, the authors have some practical holiday exercise tips. "It is important to stress that when you start exercising, ... read more

How to reap the benefits of exercise: It's in the genes

Exercise triggers TFEB entering ... "Our discovery of a central pathway that regulates muscle metabolism, use of glucose and mitochondrial function may have important implications in the study of ... read more



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