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Enlisting Our Own Germs to Help Us Battle Infections

my lab and others have found that mammals also encode these health-promoting mechanisms that we call disease tolerance and are essential for surviving infections. Later, we found a strain of E. coli t... read more

Inflammatory molecule essential to muscle regeneration in mice, researchers find

Metabolite infiltrates muscle fiber Muscle stem cells usually nestle quietly along the muscle fibers. They spring into action when a muscle is damaged by trauma or overuse, dividing rapidly to generat... read more

Nucana Offers A Prudent Way To Invest In Cancer Cures

Fluorouracil, which was patented in 1956 and came into medical use in 1962, is on the World Health Organization's List of Essential Medicines and ... designed to overcome key cancer resistance mechani... read more

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Alternative splicing is crucial to muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute ... elegans to humans, ... read more

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The Health Benefits of Milk

How does it really improve our health? Experts share the makeup of milk and dive into ... they lost more body fat and gained more muscle mass than those who had consumed different drinks that containe... read more

Tension in axons is essential for synaptic signaling, researchers report

Every time a neuron sends a signal – to move a muscle or form a memory ... Further research is needed to identify the exact mechanism that allows this to work, he said. "This study shows that tension ... read more

Post-heart attack: How can scar tissue be turned back into healthy heart muscle?

One laboratory method to create healthy heart muscle leads to better organized sarcomeres ... Cardiomyocytes, the cells responsible for the beating of the heart, are essential to repairing the heart a... read more

How Exercise Beefs Up the Brain

Now, a research team may have finally found a molecular link between a workout and a healthy brain. Much exercise research focuses on the parts of our body that do the heavy lifting. Muscle cells ... ... read more

Researchers discover a gene that is essential for the DNA-replication process

"Our results reveal that POLD3 is essential for the stability of ... Replication is controlled by redundant mechanisms; for example, the loss of one of the two copies of the genes that generate these ... read more

Protecting people from the financial consequences of health-care payments

Pooling and pre-payment mechanisms key to universal ... of funds in an integrated national health financing strategy is essential for progress, particularly in countries that lack the fiscal capacity ... read more

Stem cell aging: mechanisms, regulators and therapeutic opportunities

Furthermore, such knowledge will be essential to inform development ... diminishing the regenerative capacity of muscle stem cells as a consequence of replicative aging 134. By analogy, repeated deman... read more

Do Statins Make It Tough to Exercise?

And their mitochondria, tiny mechanisms within cells that generate power ... (People generally dislike muscle biopsies.) But an eye-opening 2005 study of healthy young people taking statins showed tha... read more



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