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Diminished Conditioned Pain Modulation Observed In Patients With Ibs - Latest News


New research reveals effective treatments for gastrointestinal conditions

Patients answered questions about their health-related quality of life in five areas: mobility, self care, usual activities, pain/discomfort and anxiety ... that some probiotics help people with ... read more

Studies examine potential treatments for UC, hep C and other gastrointestinal conditions

Patients answered questions about their health-related quality of life in five areas: mobility, self care, usual activities, pain/discomfort and anxiety ... that some probiotics help people with ... read more

Nocebo effects in clinical studies: hints for pain therapy

4,34 The implications for patients who depend on pharmacological management of pain are extremely relevant, especially if diminished medication efficacy ... communication on the placebo effect in ... read more

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Why trials of autism treatments have a placebo problem

Placebos are not new: Hippocrates, the father of medicine, observed them; Avicenna ... In trials of people suffering from conditions such as chronic pain, irritable bowel syndrome or depression, ... read more


Nocebos in rheumatology: emerging concepts and their implications for clinical practice

... or physiological condition that occur because of the patient’s negative anticipation of treatment, and might result in suboptimal outcomes and non-adherence. Nocebo effects are observed in ... read more

Acute physiological and electrical accentuation of vagal tone has no effect on pain or gastrointestinal motility in chronic pancreatitis

conditioned pain modulation (CPM) and assessments of gastroduodenal motility with ultrasound were performed. Conclusion: This explorative study demonstrated that t-VNS and DSB increased CVT in ... read more

Management of Opioid Analgesic Overdose

acetaminophen (including products coformulated with acetaminophen), and illicit substances and determine whether the patient has had contact with anyone receiving pharmacologic treatment for chronic ... read more

Observe to get pain relief: current evidence and potential mechanisms of socially learned pain modulation

18,42,48 In this review, we used both terms “social” and “observational” learning to allude to the pain modulation that a study participant or patient experiences ... Corey LA. Irritable bowel ... read more

Lost but making progress—Where will new analgesic drugs come from?

mechanistic phenotyping of pain patients, development of biomarkers, and emerging insights into chronic pain as a disorder of both the periphery and the brain. Collaborative efforts between ... read more

Getting the pain you expect: mechanisms of placebo, nocebo and reappraisal effects in humans

The perception of pain is ... is limited in patient placebo studies, a report showing a positive correlation between blood flow increases in the right vlPFC after placebo treatment and symptom ... read more

For Placebo Effects in Medicine, Seeing Is Believing

The regions of the brain that are activated by the pain stimulus are shown in red. Activation in these brain regions is diminished commensurate ... single-blind RCT conducted with patients suffering ... read more



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