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Diminished Conditioned Pain Modulation Observed In Patients With Ibs - Latest News


Nocebo effects in clinical studies: hints for pain therapy

4,34 The implications for patients who depend on pharmacological management of pain are extremely relevant, especially if diminished medication efficacy ... communication on the placebo effect in irri... read more

Central pain processing is altered in people with Achilles tendinopathy

Results An increase in PPT was observed in the Achilles tendinopathy ... Considering the presence of altered conditioned pain modulation effects in people with Achilles tendinopathy, similar findings ... read more

Central processing of rectal pain in patients with irritable bowel syndrome: an fMRI study

It may not be excluded, however, that attentional modulation might have contributed to the variability observed ... IBS patients remains an open question. In conclusion, this fRMI study has indicated ... read more

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For Placebo Effects in Medicine, Seeing Is Believing

The regions of the brain that are activated by the pain stimulus are shown in red. Activation in these brain regions is diminished commensurate ... single-blind RCT conducted with patients suffering f... read more


Nicotine and Tobacco as Substances of Abuse in Children and Adolescents

Users also report that smoking alleviates anxiety, depression, and pain and that they, therefore ... 22 Neurophysiologic dependence may lead to tolerance, with a diminished effect experienced with con... read more

Observe to get pain relief: current evidence and potential mechanisms of socially learned pain modulation

18,42,48 In this review, we used both terms “social” and “observational” learning to allude to the pain modulation that a study participant or patient experiences ... Corey LA. Irritable bowel syndrom... read more

Failure of Extinction of Fear Responses in Posttraumatic Stress Disorder: Evidence From Second-Order Conditioning

The authors used event-related potentials of electroencephalogram (EEG), self-report measures, skin conductance responses, heart rate, and startle modulation to assess the differential conditioned ... ... read more

Translational approaches to treatment-induced symptoms in cancer patients

Cancer therapy makes patients sick ... emesis and pain. However, this is not the case for a number of other symptoms that include fatigue, distractibility, poor memory, and diminished interest in prev... read more

Dr. Philippe Richebe

Dr. Philippe Richebe is an anesthesiologist in Seattle, Washington and is affiliated with multiple hospitals in the area, including University of Washington Medical Center and Virginia Mason Medical C... read more

Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen–specific CTLs

1 Department of Neurosurgery, Duke University School of Medicine, Durham, NC 27710, USA. 2 Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA. 3 Department of Molecular G... read more

Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury

Although, in both NP and AF tissues, the proportion of C4S tended to be higher in the injury groups than in the control groups, no significant differences were observed ... pain phenotype, enabling us ... read more

Dissociating Pain from Its Anticipation in the Human Brain

Anticipation of pain can in its own right cause mood changes and behavioral adaptations that exacerbate the suffering experienced by chronic pain patients. Selective manipulations ... of somatosensory ... read more



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