Clinical Outcomes For Patients With Gleason Score 10 Prostate Adenocarcinoma: Results From A Multiinstitutional Consortium Study | Latest News RSS feed

Clinical Outcomes For Patients With Gleason Score 10 Prostate Adenocarcinoma: Results From A Multiinstitutional Consortium Study - Latest News


Active Surveillance for Prostate Cancer: How to Do It Right

[19] This single-arm cohort study included 993 men, 740 with low-risk disease (Gleason score ≤ 6 and serum PSA level ≤ 10 ng ... et al. Patient-specific meta-analysis of 2 clinical validation studies ... read more

Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?

Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score ... by study investigators. Through systematic me... read more

Intermediate-Risk Patients With Organ-Confined Prostate Cancer Have High Cancer-Free Survival Rate After Stereotactic Body Radiation Therapy

The phase II, prospective, multi-institutional study ... risk patients (CS T1c-T2b, N0-x, M0-x, with either Gleason = 7 & PSA less than 10 ng/ml, or Gleason less than or equal to 6 & PSA between 10-20 ... read more

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Why Genomic Health Is A Solid Long-Term Buy

The test results are reported as a Genomic Prostate Score ... patients; specifically, treatment intensity decreased for 28% of patients and increased for 10% of patients. The U.S. study conducted in c... read more


Men with low-/intermediate-risk prostate cancer benefit from fewer, higher-dose radiation treatments

"However, because prostate ... outcomes they would receive from a longer course of treatment." This multi-institutional consortium study—to date the largest analysis of long-term outcomes following SB... read more

Favorable vs Unfavorable Intermediate-Risk Prostate Cancer: A Review of the New Classification System and Its Impact on Treatment Recommendations

Reese and colleagues analyzed the heterogeneity of the NCCN prostate cancer risk groups by investigating whether the outcomes of patients ... clinical stage, and Gleason score to predict pathological ... read more

Treatment of localized prostate cancer: when is active surveillance appropriate?

For men harboring tumors with a Gleason score >7, data from two recently reported Swedish trials suggest lower prostate ... of a patient's diagnosis when interpreting results from the medical literatu... read more

Multi-institutional outcomes following LDR brachytherapy in patients with higher-risk prostate cancer.

Background: We report the outcomes for a cohort of men with higher risk prostate adenocarcinoma ... from a multi-institutional database. Higher risk was defined as patients with ≥ 2 D’Amico intermedia... read more

Systematic overview of the evidence for brachytherapy in clinically localized prostate cancer

Results in patients with favourable tumours (T1 or T2 tumour, Gleason score of 6 or lower, serum PSA level of 10 ng/mL [μg/L ... PSA level influence the outcome of any definitive treatment of localize... read more

Transcatheter Aortic-Valve Replacement with a Self-Expanding Prosthesis

We recruited patients with severe aortic stenosis who were at increased surgical risk as determined by the heart team at each study ... clinical end points, which are based on the definitions establis... read more

Intermediate risk prostate cancer may be well controlled with brachytherapy alone

NRG Oncology/RTOG 0232 is a phase III, multi-institutional ... (i.e., clinical stage T1c-T2b) and enrolled in the trial between 2003 and 2012. Prostate cancer risk groups are assigned based on the pro... read more

Evolution of advanced technologies in prostate cancer radiotherapy

Conventional treatment options for clinically localized, low-risk prostate cancer include ... hypofractionated EBRT and SBRT. The clinical implementation of IMRT involves many technical factors that c... read more



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