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Hormonal Mechanism Could Explain Canagliflozin's Fracture Risk - Latest News


Mechanisms found to explain atypical femoral fractures

Our work explains some of the underlying mechanisms of AFFs and can inform the refinement of dosing schedules for patients at risk of fragility fractures.” Among the collaborators were Dr. Joseph M. L... read more

Side effects explained: Why common drugs can lead to broken bones

New research helps to explain why some commonly used drugs come with a serious ... and in that case their systemic fracture risk doubles," said Jan Tuckermann of the Fritz-Lipmann Institute. "For a yo... read more

Childhood Trauma And Its Lifelong Health Effects More Prevalent Among Minorities

Studies have linked a greater number of ACEs with greater risk of heart disease, cancer, bone fractures and chronic ... the social and biological mechanisms that might explain how highly stressful exp... read more

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The vitamin D paradox in Black Americans

Instead, vitamin D is converted to a pre-hormone ... could fully explain the significance of low measures of vitamin D status with respect to skeletal health in Black Americans. A better understanding ... read more


Older bereaved 'die of broken immune system not broken heart'

The adrenal glands produce the stress hormone cortisol, an immune suppressor which ... and combines with immune ageing to further suppress immune function, which may help to explain increased risk of ... read more

High-tech imaging could reveal mysteries of bone damage in kids with chronic disease

Walking him back to the waiting room, she asked how he wanted to explain the images to his mom ... with kidney disease have thin bones with low density and increased risk of fracture. Today, Leonard’s ... read more

Why Doesn't Science Understand the Menopause?

It did, once I finally went on hormone replacement therapy (HRT ... to protect the endometrium: though the mechanism is unclear, adding oestrogen without a progestational agent increases the risk of e... read more

What not to do in a disaster

It’s the same mechanism across the animal kingdom ... Another 40 (mostly sprains and fractures) had occurred while the victim was rushing to the sealed room. What was going on? Even at the best of tim... read more

Happy hormone's calcium connection may make cows and humans healthier

In fact, non-lactating women, men and children who take SSRIs show signs of increased fracture risk ... could then be further exacerbated if the mother is taking an SSRI. Fortunately, Hernandez's rese... read more

Passport to the murky world of contraceptives for housemaids

“Some of the disease conditions contraindicating this injection are migraine, headache, women at high risk ... they could clearly state that the medical screening is limited to the guidelines stated a... read more



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