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Hormonal Mechanism Could Explain Canagliflozin's Fracture Risk - Latest News


Mechanisms found to explain atypical femoral fractures

Our work explains some of the underlying mechanisms of AFFs and can inform the refinement of dosing schedules for patients at risk of fragility fractures.” Among the collaborators were Dr. Joseph M. L... read more

Blocking Cell Signals Points to Possible Treatment for Osteoporosis

Cells in the brain may play a role in regulating bone density in women, which could ... to causes fractures from minor stresses, such as falls. After menopause, they are at higher risk than men for os... read more

Optimal Use of Bone-Targeted Agents in Breast Cancer

[2-4] Herein, we will attempt to explain why this may be the case. Prevention of Bone Loss Induced by Aromatase Inhibitor Therapy Patients with hormone receptor ... women at high risk for breast cance... read more

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Side effects explained: Why common drugs can lead to broken bones

New research helps to explain why some commonly used drugs come with a serious ... and in that case their systemic fracture risk doubles," said Jan Tuckermann of the Fritz-Lipmann Institute. "For a yo... read more


Mechanisms for optimal health…for all athletes!

To explain the mechanism behind this observation, a peptide hormone leptin is secreted by adipose tissue ... Low age matched BMD in athletes is of concern as this increases risk of stress fracture. In ... read more

High-tech imaging could reveal mysteries of bone damage in kids with chronic disease

Walking him back to the waiting room, she asked how he wanted to explain the images to his mom ... with kidney disease have thin bones with low density and increased risk of fracture. Today, Leonard’s ... read more

The vitamin D paradox in Black Americans

Instead, vitamin D is converted to a pre-hormone ... could fully explain the significance of low measures of vitamin D status with respect to skeletal health in Black Americans. A better understanding ... read more

Older bereaved 'die of broken immune system not broken heart'

(PhysOrg.com) -- Immunity experts at the University of Birmingham have found biological evidence to suggest that bereavement lowers physical immunity, putting older people at risk ... Older bereaved ' ... read more

Why Doesn't Science Understand the Menopause?

It did, once I finally went on hormone replacement therapy (HRT ... to protect the endometrium: though the mechanism is unclear, adding oestrogen without a progestational agent increases the risk of e... read more

Childhood Trauma And Its Lifelong Health Effects More Prevalent Among Minorities

Studies have linked a greater number of ACEs with greater risk of heart disease, cancer, bone fractures and chronic ... the social and biological mechanisms that might explain how highly stressful exp... read more

What not to do in a disaster

It’s the same mechanism across the animal kingdom ... Another 40 (mostly sprains and fractures) had occurred while the victim was rushing to the sealed room. What was going on? Even at the best of tim... read more

Happy hormone’s calcium connection may make cows and humans healthier

In fact, non-lactating women, men and children who take SSRIs show signs of increased fracture risk and increased ... species helps to explain bone loss and uncover possible treatments. “We’re looking ... read more



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