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Cellular reprogramming approach promotes muscle regeneration in injured mice

IMPCs stained for markers of muscle stem, progenitor and differentiated cells. iMPCs recapitulate muscle differentiation in a dish. Credit: Ori Bar-Nur and Mattia Gerli Scientists in the United States have developed a simple and robust approach for ... read more

U.S. scientists use cellular reprogramming approach to promote muscle regeneration

American scientists have developed a simple and robust approach for directly reprogramming mature skin cells into ... into mice with leg injuries, the iMPCs engrafted in the damaged tissue and contributed to sustained muscle regeneration, according to ... read more

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

The adult mammalian heart cannot efficiently generate new cardiac muscle cells in response to injury, and although ... strategies to simultaneously promote reprogramming and proliferation. Thus, to enhance heart regeneration, it will be important to ... read more

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Scientists turn skin cells into heart, brain cells using drugs

An alternative approach used genes to convert scar-forming cells in the heart of animals into new muscle ... brain injury. "Our hope is to one day treat diseases like heart failure or Parkinson's disease with drugs that help the heart and brain regenerate ... read more

Skin cells turned into heart and brain cells

"Reprogramming ... new muscle that improved the function of the heart, using a chemical reprogramming approach. The team conducted two studies using a cocktail of nine chemicals to change human skin cells into beating heart cells and brain cells. read more

Cellular reprogramming approach promotes muscle regeneration in injured mice

Scientists in the United States have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells. By combining transient expression of a protein called MyoD and treatment with three small molecules, the ... read more

U.S. scientists use cellular reprogramming approach to promote muscle regeneration

WASHINGTON, May 8 (Xinhua) -- American scientists have developed a simple and robust approach for directly reprogramming mature skin cells ... mice with leg injuries, the iMPCs engrafted in the damaged tissue and contributed to sustained muscle ... read more

Cellular reprogramming promotes muscle regeneration in injured mice

Scientists have developed a simple and robust approach for directly reprogramming ... skeletal muscle stem cells. When transplanted into mice with leg injuries, the iMPCs engrafted in the damaged tissue and contributed to sustained muscle regeneration. “ read more


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