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Cellular Reprogramming Approach Promotes Muscle Regeneration In Injured Mice - Latest News


Cellular reprogramming approach promotes muscle regeneration in injured mice

Scientists in the United States have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells. By combining transient expression of a protein call... read more

U.S. scientists use cellular reprogramming approach to promote muscle regeneration

American scientists have developed a simple and robust approach for directly reprogramming mature skin cells into ... into mice with leg injuries, the iMPCs engrafted in the damaged tissue and contrib... read more

Cellular Reprogramming Rejuvenates Old Mice and Boosts Lifespans 30%

To see if the approach was isolated to mice with progeria, the researchers then tested it on normal middle-aged mice. They found that partial reprogramming enhanced the regeneration of muscle tissue a... read more

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Researchers utilize genetically corrected stem cells to spark muscle regeneration

Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration ... mice, generatin... read more


Cardiac regeneration strategies: Staying young at heart

1 Department of Molecular Cell Biology, Weizmann Institute of Science ... been found to display robust heart regeneration at the adult stage (2). Fetal and neonatal mice also respond constructively to ... read more

Aging Muscles May Be Restored by Discovery of a Key to Making Muscle

First, when muscle is damaged by injury or degenerative ... the pool of satellite cells and promote their differentiation into muscle fibers," said Alessandra Sacco, Ph.D., assistant professor in the ... read more

Bioreactor device helps frogs regenerate their legs

Their findings, appearing November 6 in the journal Cell Reports ... inducing spinal cord regeneration and tumor reprogramming. They also hope to replicate their bioreactor experiment in mammals. Prev... read more

Penn Researchers Develop an Injectable Gel that Helps Heart Muscle Regenerate after a Heart Attack

In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury ... maybe a week or two after injury,” Morrisey said. “We want to promote pr... read more

U.S. scientists use cellular reprogramming approach to promote muscle regeneration

WASHINGTON, May 8 (Xinhua) -- American scientists have developed a simple and robust approach for directly reprogramming mature skin cells ... mice with leg injuries, the iMPCs engrafted in the damage... read more

Harnessing the immune response to improve functional healing

A majority of tissue engineering approaches rely on stem cells and/or growth factors to promote ... of injury. To determine the impact of IL-4 on tissue regeneration, IL-4–conjugated gold nanoparticle... read more

Cellular reprogramming approach promotes muscle regeneration in injured mice

IMPCs stained for markers of muscle stem, progenitor and differentiated cells. iMPCs recapitulate muscle differentiation in a dish. Credit: Ori Bar-Nur and Mattia Gerli Scientists in the United States ... read more



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