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Cellular Reprogramming Approach Promotes Muscle Regeneration In Injured Mice - Latest News


Cellular reprogramming approach promotes muscle regeneration in injured mice

Scientists in the United States have developed a simple and robust approach for directly reprogramming mature skin cells into immature muscle cells. By combining transient expression of a protein ... read more

U.S. scientists use cellular reprogramming approach to promote muscle regeneration

American scientists have developed a simple and robust approach for directly reprogramming mature skin cells into ... into mice with leg injuries, the iMPCs engrafted in the damaged tissue and ... read more

New technique promotes dramatic increase in cardiac function

Fibroblasts account for a majority of cells in the heart and are activated following injury to form this fibrotic scar tissue. Fibrosis impedes regeneration ... to promote new muscle formation, while ... read more

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Reprogramming Surge Resets Biological Clock in Animals

That would seem to be the lesson from a new study by Salk Institute researchers, who found that a brief burst of cellular reprogramming ... regeneration capacity of pancreas and muscle. In this case, ... read more


Heart Damage Repaired By Reprogramming Resident Fibroblasts into Functioning Heart Cells

Fibroblasts account for a majority of cells in the heart and are activated following injury to form this fibrotic scar tissue. Fibrosis impedes regeneration ... to promote new muscle formation, while ... read more

Cardiac regeneration strategies: Staying young at heart

Whereas damaged skeletal muscle has a profound capacity to regenerate, heart muscle, at least in mammals, has poor regenerative potential. This deficiency is attributable to the lack of resident ... read more

Cellular reprogramming slows aging in mice

Previous efforts resulted in mice that either died immediately or developed extensive tumors. The Salk team used a partial cellular reprogramming approach ... of injury in mice. In this study, partial ... read more

Corrected Induced Pluripotent Stem Cells Spark Muscle Regeneration

Researchers have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in ... well in the dystrophic mice, generating functional muscle and ... read more

An injectable gel that helps heart muscle regenerate after heart attack

In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury ... stimulus —maybe a week or two after injury," Morrisey said. "We want to ... read more

Heart muscle regeneration: the wonder of a Cardio-Cocktail

Strategies for achieving heart regeneration fall into three main categories: 1) providing exogenous pools of stem cells, 2) reprogramming cardiac ... function following myocardial injury. Myocardial ... read more

Chip Reprograms Skin into Any Cell Type

The noninvasive tissue nanotransfection (TNT) technology has already been used in mice ... reprogramming, not just cell reprogramming,” Dr. Sen stressed as he spoke with GEN. “Our technology rescued ... read more



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