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AMPK Activator O304 A Novel Potential Treatment For Diabetic Kidney Disease - Latest News


AMPK Activator O304 A Novel Potential Treatment for Diabetic Kidney Disease

Globally ~40% of type 2 diabetes (T2D) patients develop diabetic kidney disease (DKD), and diabetes is the leading cause of end stage renal disease, requiring dialysis or a kidney transplant. Standard ... read more

New pathway towards treatments for inflammatory diseases

A molecule thought to play a key role in some inflammatory diseases can be ... Indeed, as AMPK is known to be stimulated by a number of existing anti-diabetic drugs, these should be investigated as po... read more

Obesity, oxidative stress, and fibrosis in chronic kidney disease

E-mail: kumarsharma@ucsd.edu Obesity in combination with diabetes and hypertension likely is contributing to the increasing incidence of chronic kidney disease (CKD) in the 21st century worldwide and ... read more

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Metformin Reverses Established Lung Fibrosis

Researchers at the University of Alabama at Birmingham have shown — for the first time — that established lung fibrosis can be reversed using a drug treatment ... dependent diabetes. The research focu... read more

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Effectiveness of canagliflozin in treating type 2 diabetes

may be particularly effective in treatment of type 2 diabetes. "We have found that canagliflozin not only inhibits SGLT2 but also activates the AMP-activated protein kinase (AMPK), a signalling pathwa... read more

Poxel's Anti-diabetic Imeglimin Confirms Its Unique Mechanism of Action in Type 2 Diabetic Patients

No other single agent impacts the three main organs involved in this chronic disease, which means Imeglimin can be combined with any current diabetes treatments. This potential was ... A direct activa... read more

AMPK Activator O304 A Novel Potential Treatment for Diabetic Kidney Disease

Globally ~40% of type 2 diabetes (T2D) patients develop diabetic kidney disease (DKD), and diabetes is the leading cause of end stage renal disease, requiring dialysis or a kidney transplant. Standard ... read more

Proteostasis in endoplasmic reticulum—new mechanisms in kidney disease

Both pathways are rapidly activated and crosstalk with each other when cells ... associated with the development and progression of various diseases, including kidney disease. 6 The UPR pathway is the ... read more

MAGE Genes Provide Insight Into Optimizing Chemotherapy, Cancer Researchers Find

Researchers found that these genes have an effect on a protein called AMPK, offering valuable ... the whole patient with innovative treatments, while fostering groundbreaking basic research that has t... read more



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